Go Back
Delicious Cattle Drive Casserole served in a rustic dish, perfect for hearty meals.

Cattle Drive Casserole

A hearty and comforting Southwest-inspired dish with ground beef, vegetables, and a cheesy biscuit-like crust, perfect for feeding a crowd or meal prep.
Prep Time 10 minutes
Cook Time 40 minutes
Total Time 50 minutes
Course Dinner, Main Course
Cuisine American, Southwestern
Servings 8 servings
Calories 400 kcal

Ingredients
  

For the casserole

  • 1.5 pounds Lean Ground Beef
  • 1 count Red Bell Pepper, seeded and chopped
  • 1 count Yellow Onion, chopped
  • 1 ounce Taco Seasoning Mix
  • 2.5 cups Biscuit Mix, like Bisquick
  • 1 cup Water
  • 1 can Cooking Spray, like Pam
  • 0.5 cup Sour Cream
  • 0.5 cup Mayonnaise
  • 4 ounces Diced Green Chiles, drained
  • 1.5 cups Cheddar Cheese, Fiesta Blend, shredded, divided
  • 1 teaspoon Garlic Powder
  • 0.5 cup Salsa, mild

Instructions
 

Preparation

  • Preheat the oven to 350℉.
  • In a large skillet, cook the ground beef over medium-high heat until it is no longer pink, and then drain the excess fat.
  • Prepare the biscuit dough by mixing the biscuit mix and water, then press this mixture into a greased 9 x 13” casserole dish.
  • Bake for 5-8 minutes until set and lightly golden.
  • Add the chopped onions and bell pepper to the cooked beef and cook for another 4 minutes.
  • Stir in the taco seasoning and then remove from heat.
  • Spread the beef mixture evenly over the baked biscuit layer.
  • In a mixing bowl, combine sour cream, mayonnaise, drained green chiles, ¾ cup of cheese, and garlic powder.
  • Spread this mixture over the beef layer.
  • Add spoonfuls of salsa on top, and sprinkle the remaining cheese.
  • Bake uncovered for 30 minutes or until hot and bubbly.

Notes

Serve with additional toppings like chopped green onions, fresh cilantro, or jalapeños. Great alongside a side salad or cornbread.
Keyword Beef Casserole, Cattle Drive Casserole, Comfort Food, Easy Dinner